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Genetic Diseases That Predispose to Early Liver Cirrhosis
Joint Authors
Liguori, Renato
Scorza, Manuela
Castaldo, Giuseppe
Zarrilli, Federica
Amato, Felice
Elce, Ausilia
Source
International Journal of Hepatology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Inherited liver diseases are a group of metabolic and genetic defects that typically cause early chronic liver involvement.
Most are due to a defect of an enzyme/transport protein that alters a metabolic pathway and exerts a pathogenic role mainly in the liver.
The prevalence is variable, but most are rare pathologies.
We review the pathophysiology of such diseases and the diagnostic contribution of laboratory tests, focusing on the role of molecular genetics.
In fact, thanks to recent advances in genetics, molecular analysis permits early and specific diagnosis for most disorders and helps to reduce the invasive approach of liver biopsy.
American Psychological Association (APA)
Scorza, Manuela& Elce, Ausilia& Zarrilli, Federica& Liguori, Renato& Amato, Felice& Castaldo, Giuseppe. 2014. Genetic Diseases That Predispose to Early Liver Cirrhosis. International Journal of Hepatology،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-492657
Modern Language Association (MLA)
Scorza, Manuela…[et al.]. Genetic Diseases That Predispose to Early Liver Cirrhosis. International Journal of Hepatology No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-492657
American Medical Association (AMA)
Scorza, Manuela& Elce, Ausilia& Zarrilli, Federica& Liguori, Renato& Amato, Felice& Castaldo, Giuseppe. Genetic Diseases That Predispose to Early Liver Cirrhosis. International Journal of Hepatology. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-492657
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492657