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Peroxisome Dynamics : Molecular Players, Mechanisms, and (Dys)functions
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-14
Country of Publication
Egypt
No. of Pages
24
Main Subjects
Abstract EN
Peroxisomes are remarkably versatile cell organelles whose size, shape, number, and protein content can vary greatly depending on the organism, the developmental stage of the organism’s life cycle, and the environment in which the organism lives.
The main functions usually associated with peroxisomes include the metabolism of lipids and reactive oxygen species.
However, in recent years, it has become clear that these organelles may also act as intracellular signaling platforms that mediate developmental decisions by modulating extraperoxisomal concentrations of several second messengers.
To fulfill their functions, peroxisomes physically and functionally interact with other cell organelles, including mitochondria and the endoplasmic reticulum.
Defects in peroxisome dynamics can lead to organelle dysfunction and have been associated with various human disorders.
The purpose of this paper is to thoroughly summarize and discuss the current concepts underlying peroxisome formation, multiplication, and degradation.
In addition, this paper will briefly highlight what is known about the interplay between peroxisomes and other cell organelles and explore the physiological and pathological implications of this interorganellar crosstalk.
American Psychological Association (APA)
Fransen, Marc. 2012. Peroxisome Dynamics : Molecular Players, Mechanisms, and (Dys)functions. ISRN Cell Biology،Vol. 2012, no. 2012, pp.1-24.
https://search.emarefa.net/detail/BIM-492697
Modern Language Association (MLA)
Fransen, Marc. Peroxisome Dynamics : Molecular Players, Mechanisms, and (Dys)functions. ISRN Cell Biology No. 2012 (2012), pp.1-24.
https://search.emarefa.net/detail/BIM-492697
American Medical Association (AMA)
Fransen, Marc. Peroxisome Dynamics : Molecular Players, Mechanisms, and (Dys)functions. ISRN Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-24.
https://search.emarefa.net/detail/BIM-492697
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492697