Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort
Joint Authors
Macarios, David
Hochberg, Marc
Satram-Hoang, Sacha
Wade, Sally
Yurgin, Nicole
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Subject- and physician-reported data from 4,429 postmenopausal women receiving osteoporosis treatment in the Prospective Observational Scientific Study Investigating Bone Loss Experience (POSSIBLE US) were used to assess the prevalence of risk factors (RFs) and on-study fracture.
RFs assessed at study entry were age >70 years; fracture since age 50; minimum T-score (hip/spine) ≤−2.5 at diagnosis; body mass index <18.5 kg/m2; rheumatoid arthritis; parental history of hip fracture; current smoking; and recent oral glucocorticoid use.
Data were collected with semiannual self-administered questionnaires.
Results were stratified by physician-reported osteoporosis/osteopenia diagnosis.
Low T-score and age >70 years were the most common RFs in the osteoporosis group, and age >70 years and prior fracture were the most common risk factors in the osteopenia group.
Multiple RFs were more common than a single RF in osteoporotic women (54.2% versus 34.6%; P<0.0001) but not osteopenic women (13.8% versus 33.6%; P<0.0001).
Women with multiple RFs had more on-study osteoporosis-related fractures than women with a single RF (osteoporosis group: 9.9% versus 6.2%; P=0.0092; osteopenia group: 11.2% versus 4.7%; P<0.0001).
In postmenopausal women receiving osteoporosis treatment, multiple RFs increased fracture risk.
RFs, in addition to bone mineral density, can help identify candidates for osteoporosis treatment.
American Psychological Association (APA)
Yurgin, Nicole& Wade, Sally& Satram-Hoang, Sacha& Macarios, David& Hochberg, Marc. 2013. Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-492756
Modern Language Association (MLA)
Yurgin, Nicole…[et al.]. Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort. International Journal of Endocrinology No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-492756
American Medical Association (AMA)
Yurgin, Nicole& Wade, Sally& Satram-Hoang, Sacha& Macarios, David& Hochberg, Marc. Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-492756
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492756