Chemical Composition and Validation of the Ethnopharmacological Reported Antimicrobial Activity of the Body Fat of Phrynops geoffroanus Used in Traditional Medicine
Joint Authors
Cabral, Mario Eduardo Santos
Douglas Melo Coutinho, Henrique
Filho, João Antonio de Araujo
Teles, Diego Alves
Almeida, Waltécio de Oliveira
Kerntopf, Marta Regina
Dias, Diógenes de Queiroz
Alves, Romulo Romeu da Nobrega
Paiva Oliveira, Olga
Costa, José Galberto Martins da
Sales, Débora Lima
Sousa, José Guilherme Gonçalves de
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Phrynops geoffroanus is a small turtle that inhabits lakes, rivers, and streams throughout South America.
The body fat of this animal is used as a folk medicine in Brazil for treating illnesses such as sore throats, ear aches, mumps, rheumatism, and arthritis.
The present study evaluated the antimicrobial activity of oil extracted from Phrynops geoffroanus (OPG), determined its chemical composition, and discussed the implications of its use in traditional medicine.
The OPG was obtained from the ventral region of this turtle using hexane as a solvent.
The antimicrobial activity of OPG was tested against standard and multiresistance strains of bacteria and fungi and its composition was determined indirectly by analyzing the methyl esters of the component fatty acids.
The OPG presented a clinically relevant antifungal activity against Candida krusei ATCC 6258 (MIC 128 µg/mL).
When the OPG was associated with the antibacterial and antifungal drugs, was observed a synergistic effect when associated the OPG with the gentamicin against the strain Pseudomonas aeruginosa 22.
Our results indicated that OPG has clinically relevant antifungal activity against C.
krusei, and demonstrated synergetic antibacterial activity in combination with commercial antibiotics against Pseudomonas aeruginosa.
American Psychological Association (APA)
Dias, Diógenes de Queiroz& Cabral, Mario Eduardo Santos& Sales, Débora Lima& Paiva Oliveira, Olga& Filho, João Antonio de Araujo& Teles, Diego Alves…[et al.]. 2013. Chemical Composition and Validation of the Ethnopharmacological Reported Antimicrobial Activity of the Body Fat of Phrynops geoffroanus Used in Traditional Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-492760
Modern Language Association (MLA)
Dias, Diógenes de Queiroz…[et al.]. Chemical Composition and Validation of the Ethnopharmacological Reported Antimicrobial Activity of the Body Fat of Phrynops geoffroanus Used in Traditional Medicine. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-492760
American Medical Association (AMA)
Dias, Diógenes de Queiroz& Cabral, Mario Eduardo Santos& Sales, Débora Lima& Paiva Oliveira, Olga& Filho, João Antonio de Araujo& Teles, Diego Alves…[et al.]. Chemical Composition and Validation of the Ethnopharmacological Reported Antimicrobial Activity of the Body Fat of Phrynops geoffroanus Used in Traditional Medicine. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-492760
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492760