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A High Ductal Flow Velocity Is Associated with Successful Pharmacological Closure of Patent Ductus Arteriosus in Infants 22–27 Weeks Gestational Age
Joint Authors
Sindelar, Richard
Olsson, Karl Wilhelm
Jonzon, Anders
Source
Critical Care Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To identify factors affecting closure of patent ductus arteriosus (PDA) in newborn infants born at 22–27 weeks gestational age (GA) during pharmacological treatment with cyclooxygenase inhibitors.
Method.
Infants born at 22–27 weeks of GA between January 2006 and December 2009 who had been treated pharmacologically for PDA were identified retrospectively.
Medical records were assessed for clinical, ventilatory, and outcome parameters.
Echocardiographic examinations during treatment were reviewed.
Results.
Fifty-six infants were included in the study.
Overall success rate of ductal closure with pharmacological treatment was 52%.
Infants whose PDA was successfully closed had a higher GA (25+4 weeks versus 24+3 weeks; P=0.047), and a higher pretreatment left to right maximal ductal flow velocity (1.6 m/s versus 1.1 m/s; P=0.023).
Correcting for GA, preeclampsia, antenatal steroids, and age at start of treatment, a higher maximal ductal flow velocity was still associated with successful ductal closure (OR 3.04; P=0.049).
Conclusion.
Maximal ductal flow velocity was independently associated with success of PDA treatment.
American Psychological Association (APA)
Olsson, Karl Wilhelm& Jonzon, Anders& Sindelar, Richard. 2012. A High Ductal Flow Velocity Is Associated with Successful Pharmacological Closure of Patent Ductus Arteriosus in Infants 22–27 Weeks Gestational Age. Critical Care Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-492786
Modern Language Association (MLA)
Olsson, Karl Wilhelm…[et al.]. A High Ductal Flow Velocity Is Associated with Successful Pharmacological Closure of Patent Ductus Arteriosus in Infants 22–27 Weeks Gestational Age. Critical Care Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-492786
American Medical Association (AMA)
Olsson, Karl Wilhelm& Jonzon, Anders& Sindelar, Richard. A High Ductal Flow Velocity Is Associated with Successful Pharmacological Closure of Patent Ductus Arteriosus in Infants 22–27 Weeks Gestational Age. Critical Care Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-492786
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492786