A New Candidate Supporting Drug, Rikkunshito, for the QOL in Advanced Esophageal Cancer Patients with Chemotherapy Using Docetaxel5-FUCDDP
Joint Authors
Takachi, Hirokazu
Yoshida, Takahiro
Kawakita, Naoya
Tangoku, Akira
Sawada, Toru
Seike, Junichi
Yuasa, Yasuhiro
Yamai, Hiromichi
Yamamoto, Yota
Source
International Journal of Surgical Oncology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
Docetaxel/5-FU/CDDP (DFP) therapy is a useful treatment for advanced esophageal cancer.
However, adverse reactions such as chemotherapy-induced nausea and vomiting (CINV) interfere often with continuation of the chemotherapy.
We investigated the efficacy of rikkunshito (TJ-43) on CINV.
Methods.
Nineteen patients who were going to undergo DFP therapy were enrolled.
They were assigned to the following two groups: a TJ-43-treated group and -nontreated group.
The following parameters were compared between the 2 groups: (1) the frequency of symptoms occurred, (2) vomiting, nausea, and anorexia score, and (3) QOL score.
Results.
The incidence of symptoms was lower in the TJ-43-treated group than that in the control group.
The nausea score of the TJ-43-treated group was significantly lower than that of the control group.
In the QOL score, the mood score and the ADL score decreased significantly in the control group.
Conclusion.
We recommend TJ-43 administration in patients undergoing DFP chemotherapy.
American Psychological Association (APA)
Seike, Junichi& Sawada, Toru& Kawakita, Naoya& Yamamoto, Yota& Yuasa, Yasuhiro& Yamai, Hiromichi…[et al.]. 2011. A New Candidate Supporting Drug, Rikkunshito, for the QOL in Advanced Esophageal Cancer Patients with Chemotherapy Using Docetaxel5-FUCDDP. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-492815
Modern Language Association (MLA)
Seike, Junichi…[et al.]. A New Candidate Supporting Drug, Rikkunshito, for the QOL in Advanced Esophageal Cancer Patients with Chemotherapy Using Docetaxel5-FUCDDP. International Journal of Surgical Oncology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-492815
American Medical Association (AMA)
Seike, Junichi& Sawada, Toru& Kawakita, Naoya& Yamamoto, Yota& Yuasa, Yasuhiro& Yamai, Hiromichi…[et al.]. A New Candidate Supporting Drug, Rikkunshito, for the QOL in Advanced Esophageal Cancer Patients with Chemotherapy Using Docetaxel5-FUCDDP. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-492815
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492815