Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases
Joint Authors
Roniotis, Alexandros
Zervakis, Michalis
Manikis, Georgios C.
Marias, Kostas
Sakkalis, Vangelis
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Applying diffusive models for simulating the spatiotemporal change of concentration of tumour cells is a modern application of predictive oncology.
Diffusive models are used for modelling glioblastoma, the most aggressive type of glioma.
This paper presents the results of applying a linear quadratic model for simulating the effects of radiotherapy on an advanced diffusive glioma model.
This diffusive model takes into consideration the heterogeneous velocity of glioma in gray and white matter and the anisotropic migration of tumor cells, which is facilitated along white fibers.
This work uses normal brain atlases for extracting the proportions of white and gray matter and the diffusion tensors used for anisotropy.
The paper also presents the results of applying this glioma model on real clinical datasets.
American Psychological Association (APA)
Roniotis, Alexandros& Marias, Kostas& Sakkalis, Vangelis& Manikis, Georgios C.& Zervakis, Michalis. 2012. Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-492842
Modern Language Association (MLA)
Roniotis, Alexandros…[et al.]. Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-492842
American Medical Association (AMA)
Roniotis, Alexandros& Marias, Kostas& Sakkalis, Vangelis& Manikis, Georgios C.& Zervakis, Michalis. Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-492842
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492842