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Circadian Rhythm Disturbances in Patients with Alzheimer's Disease : A Review
Joint Authors
Weldemichael, Dawit A.
Grossberg, George T.
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Circadian Rhythm Disturbances (CRDs) affect as many as a quarter of Alzheimer's disease (AD) patients during some stage of their illness.
Alterations in the suprachiasmatic nucleus and melatonin secretion are the major factors linked with the cause of CRDs.
As a result, the normal physiology of sleep, the biological clock, and core body temperature are affected.
This paper systematically discusses some of the causative factors, typical symptoms, and treatment options for CRDs in patients with AD.
This paper also emphasizes the implementation of behavioral and environmental therapies before embarking on medications to treat CRDs.
Pharmacotherapeutic options are summarized to provide symptomatic benefits for the patient and relieve stress on their families and professional care providers.
As of today, there are few studies relative to CRDs in AD.
Large randomized trials are warranted to evaluate the effects of treatments such as bright light therapy and engaging activities in the reduction of CRDs in AD patients.
American Psychological Association (APA)
Weldemichael, Dawit A.& Grossberg, George T.. 2010. Circadian Rhythm Disturbances in Patients with Alzheimer's Disease : A Review. International Journal of Alzheimer's Disease،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-492907
Modern Language Association (MLA)
Weldemichael, Dawit A.& Grossberg, George T.. Circadian Rhythm Disturbances in Patients with Alzheimer's Disease : A Review. International Journal of Alzheimer's Disease No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-492907
American Medical Association (AMA)
Weldemichael, Dawit A.& Grossberg, George T.. Circadian Rhythm Disturbances in Patients with Alzheimer's Disease : A Review. International Journal of Alzheimer's Disease. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-492907
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492907