Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage
Joint Authors
Manfellotto, Dario
De Felice, Giovanna
Moretti, Costanzo
Lazzarin, Natalia
Vaquero, Elena
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
It has been twenty years since the first paper reporting the association between thyroid antibodies (TAIs) and spontaneous miscarriage was published.
Following this observation, several studies have clearly demonstrated an increased prevalence of TAI in patients with recurrent miscarriage (RM).
However, the exact mechanism underlying this association remains a matter of debate.
The aim of the present study was to evaluate the thyroid function, throughout a specific test, in patient with RM and TAI focusing on the hypothesis that TAI should be an indirect sign of a mild thyroid dysfunction.
46 patients with RM and TAI were included in the study.
All patients underwent short TRH stimulation test showing an abnormal response in the vast majority of cases (65%).
Normal FT4 and FT3 mean values were found whereas TSH values were in the upper normal range (2.64±1.3 mUI/L).
Our data support the hypothesis that in patients with RM the presence of TAI is an indirect sign of a subtle thyroid dysfunction detectable by a specific test.
This test give the possibility to identify women with RM in which specific therapeutic approaches could effectively improve the possibility for a successful pregnancy.
American Psychological Association (APA)
Lazzarin, Natalia& Moretti, Costanzo& De Felice, Giovanna& Vaquero, Elena& Manfellotto, Dario. 2012. Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-492972
Modern Language Association (MLA)
Lazzarin, Natalia…[et al.]. Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage. International Journal of Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-492972
American Medical Association (AMA)
Lazzarin, Natalia& Moretti, Costanzo& De Felice, Giovanna& Vaquero, Elena& Manfellotto, Dario. Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-492972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492972