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Finger Tapping Clinimetric Score Prediction in Parkinson's Disease Using Low-Cost Accelerometers
Joint Authors
Sharei, Hoda
Ambroise, Jérome
Crémers, Julien
Macq, Benoît
Delvaux, Valérie
Garraux, Gaëtan
Stamatakis, Julien
Source
Computational Intelligence and Neuroscience
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-16
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The motor clinical hallmarks of Parkinson's disease (PD) are usually quantified by physicians using validated clinimetric scales such as the Unified Parkinson's Disease Rating Scale (MDS-UPDRS).
However, clinical ratings are prone to subjectivity and inter-rater variability.
The PD medical community is therefore looking for a simple, inexpensive, and objective rating method.
As a first step towards this goal, a triaxial accelerometer-based system was used in a sample of 36 PD patients and 10 age-matched controls as they performed the MDS-UPDRS finger tapping (FT) task.
First, raw signals were epoched to isolate the successive single FT movements.
Next, eighteen FT task movement features were extracted, depicting MDS-UPDRS features and accelerometer specific features.
An ordinal logistic regression model and a greedy backward algorithm were used to identify the most relevant features in the prediction of MDS-UPDRS FT scores, given by 3 specialists in movement disorders (SMDs).
The Goodman-Kruskal Gamma index obtained (0.961), depicting the predictive performance of the model, is similar to those obtained between the individual scores given by the SMD (0.870 to 0.970).
The automatic prediction of MDS-UPDRS scores using the proposed system may be valuable in clinical trials designed to evaluate and modify motor disability in PD patients.
American Psychological Association (APA)
Stamatakis, Julien& Ambroise, Jérome& Crémers, Julien& Sharei, Hoda& Delvaux, Valérie& Macq, Benoît…[et al.]. 2013. Finger Tapping Clinimetric Score Prediction in Parkinson's Disease Using Low-Cost Accelerometers. Computational Intelligence and Neuroscience،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-493009
Modern Language Association (MLA)
Stamatakis, Julien…[et al.]. Finger Tapping Clinimetric Score Prediction in Parkinson's Disease Using Low-Cost Accelerometers. Computational Intelligence and Neuroscience No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-493009
American Medical Association (AMA)
Stamatakis, Julien& Ambroise, Jérome& Crémers, Julien& Sharei, Hoda& Delvaux, Valérie& Macq, Benoît…[et al.]. Finger Tapping Clinimetric Score Prediction in Parkinson's Disease Using Low-Cost Accelerometers. Computational Intelligence and Neuroscience. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-493009
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493009