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Trace Element Status (Iron, Zinc, Copper, Chromium, Cobalt, and Nickel) in Iron-Deficiency Anaemia of Children under 3 Years
Joint Authors
Bozhinova, Atanaska Naumova
Nedkova-Kolarova, Vania Nedkova
Petkova-Marinova, Tsvetelina Valentinova
Angelova, Maria Georgieva
Loboda, Andrii Nikolaevich
Pogorielov, Maksym Vladimirovich
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aim.
To determine trace element status and aetiologic factors for development of trace elements deficiencies in children with iron-deficiency anaemia (IDA) aged 0 to 3 years.
Contingent and Methods.
30 patients of the University Hospital, Pleven, Bulgaria—I group; 48 patients of the Sumy Regional Child’s Clinical Hospital, Sumy, Ukraine—II group; 25 healthy controls were investigated.
Serum concentrations of iron, zinc, copper, chromium, cobalt, and nickel were determined spectrophotometrically and by atomic absorption spectrophotometry.
Results.
Because the obtained serum levels of zinc, copper, and chromium were near the lower reference limits, I group was divided into IA and IB.
In IA group, serum concentrations were lower than the reference values for 47%, 57%, and 73% of patients, respectively.
In IB group, these were within the reference values.
In II group, results for zinc, cobalt, and nickel were significantly lower (P<0.05), and results for copper were significantly higher in comparison to controls.
Conclusion.
Low serum concentrations of zinc, copper, cobalt, and nickel were mainly due to inadequate dietary intake, malabsorption, and micronutrient interactions in both studied groups.
Increased serum copper in II group was probably due to metabolic changes resulting from adaptations in IDA.
Data can be used for developing a diagnostic algorithm for IDA.
American Psychological Association (APA)
Angelova, Maria Georgieva& Petkova-Marinova, Tsvetelina Valentinova& Pogorielov, Maksym Vladimirovich& Loboda, Andrii Nikolaevich& Nedkova-Kolarova, Vania Nedkova& Bozhinova, Atanaska Naumova. 2014. Trace Element Status (Iron, Zinc, Copper, Chromium, Cobalt, and Nickel) in Iron-Deficiency Anaemia of Children under 3 Years. Anemia،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-493033
Modern Language Association (MLA)
Angelova, Maria Georgieva…[et al.]. Trace Element Status (Iron, Zinc, Copper, Chromium, Cobalt, and Nickel) in Iron-Deficiency Anaemia of Children under 3 Years. Anemia No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-493033
American Medical Association (AMA)
Angelova, Maria Georgieva& Petkova-Marinova, Tsvetelina Valentinova& Pogorielov, Maksym Vladimirovich& Loboda, Andrii Nikolaevich& Nedkova-Kolarova, Vania Nedkova& Bozhinova, Atanaska Naumova. Trace Element Status (Iron, Zinc, Copper, Chromium, Cobalt, and Nickel) in Iron-Deficiency Anaemia of Children under 3 Years. Anemia. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-493033
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493033