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Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications
Joint Authors
Ogawa, Kohei
Ozawa, Kazue
Kasahara, Mureo
Takai, Kenji
Takada, Yasutsugu
Ono, Masako
Fukushima, Masanori
Sato, Hiroshi
Inaba, Kayo
Egawa, Hiroto
Tanaka, Koichi
Uemoto, Shinji
Teramukai, Satoshi
Source
Clinical and Developmental Immunology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
To clarify the role of CD8+ effector T cells for infectious complications, 92 recipients were classified according to the hierarchical clustering of preoperative CD8+CD45 isoforms: Group I was naive, Group II was effector memory, and Group III was effector (E) T cell-dominant.
The posttransplant infection rates progressively increased from 29% in Group I to 64.3% in Group III recipients.
The posttransplant immune status was compared with the pretransplant status, based on the measure (% difference) and its graphical form (scatter plot).
In Groups I and II, both approaches showed a strong upward deviation from pretransplant status upon posttransplant infection, indicating an enhanced clearance of pathogens.
In Group III, in contrast, both approaches showed a clear downward deviation from preoperative status, indicating deficient cytotoxicity.
The % E difference and scatter plot can be used as a useful indicator of a posttransplant infectious complication.
American Psychological Association (APA)
Uemoto, Shinji& Ozawa, Kazue& Egawa, Hiroto& Takada, Yasutsugu& Sato, Hiroshi& Teramukai, Satoshi…[et al.]. 2008. Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications. Clinical and Developmental Immunology،Vol. 2008, no. 2008, pp.1-13.
https://search.emarefa.net/detail/BIM-493063
Modern Language Association (MLA)
Uemoto, Shinji…[et al.]. Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications. Clinical and Developmental Immunology No. 2008 (2008), pp.1-13.
https://search.emarefa.net/detail/BIM-493063
American Medical Association (AMA)
Uemoto, Shinji& Ozawa, Kazue& Egawa, Hiroto& Takada, Yasutsugu& Sato, Hiroshi& Teramukai, Satoshi…[et al.]. Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications. Clinical and Developmental Immunology. 2008. Vol. 2008, no. 2008, pp.1-13.
https://search.emarefa.net/detail/BIM-493063
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493063