Refractory Anemia with Ring Sideroblasts Associated with Marked Thrombocytosis Complicated by Massive Splenomegaly Treated with Lenalidomide Resulting in Resolution of Splenomegaly but Severe and Prolonged Pancytopenia
Joint Authors
Taylor, Gordon
Culligan, Dominic
Vickers, Mark A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-07
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Refractory anemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) is a hematological malignancy that combines features of both a myeloproliferative and myelodysplastic disorder.
There have been recent reports of the successful treatment of anemia in 2 patients with RARS-T with lenalidomide.
Here we report the successful treatment of massive splenomegaly in a patient with a long history of RARS-T resulting in complete resolution of splenomegaly, but with prolonged severe cytopenias.
We also report the acquisition of the t(3;12)(q26;p13) translocation previously described in cases of myelodysplasia and the potential for transformation to myelofibrosis.
American Psychological Association (APA)
Taylor, Gordon& Culligan, Dominic& Vickers, Mark A.. 2013. Refractory Anemia with Ring Sideroblasts Associated with Marked Thrombocytosis Complicated by Massive Splenomegaly Treated with Lenalidomide Resulting in Resolution of Splenomegaly but Severe and Prolonged Pancytopenia. Case Reports in Hematology،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-493067
Modern Language Association (MLA)
Taylor, Gordon…[et al.]. Refractory Anemia with Ring Sideroblasts Associated with Marked Thrombocytosis Complicated by Massive Splenomegaly Treated with Lenalidomide Resulting in Resolution of Splenomegaly but Severe and Prolonged Pancytopenia. Case Reports in Hematology No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-493067
American Medical Association (AMA)
Taylor, Gordon& Culligan, Dominic& Vickers, Mark A.. Refractory Anemia with Ring Sideroblasts Associated with Marked Thrombocytosis Complicated by Massive Splenomegaly Treated with Lenalidomide Resulting in Resolution of Splenomegaly but Severe and Prolonged Pancytopenia. Case Reports in Hematology. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-493067
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493067