Timing Embryo Segmentation : Dynamics and Regulatory Mechanisms of the Vertebrate Segmentation Clock
Joint Authors
Resende, Tatiana P.
Andrade, Raquel P.
Palmeirim, Isabel
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-07
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
All vertebrate species present a segmented body, easily observed in the vertebrate column and its associated components, which provides a high degree of motility to the adult body and efficient protection of the internal organs.
The sequential formation of the segmented precursors of the vertebral column during embryonic development, the somites, is governed by an oscillating genetic network, the somitogenesis molecular clock.
Herein, we provide an overview of the molecular clock operating during somite formation and its underlying molecular regulatory mechanisms.
Human congenital vertebral malformations have been associated with perturbations in these oscillatory mechanisms.
Thus, a better comprehension of the molecular mechanisms regulating somite formation is required in order to fully understand the origin of human skeletal malformations.
American Psychological Association (APA)
Resende, Tatiana P.& Andrade, Raquel P.& Palmeirim, Isabel. 2014. Timing Embryo Segmentation : Dynamics and Regulatory Mechanisms of the Vertebrate Segmentation Clock. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-493097
Modern Language Association (MLA)
Resende, Tatiana P.…[et al.]. Timing Embryo Segmentation : Dynamics and Regulatory Mechanisms of the Vertebrate Segmentation Clock. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-493097
American Medical Association (AMA)
Resende, Tatiana P.& Andrade, Raquel P.& Palmeirim, Isabel. Timing Embryo Segmentation : Dynamics and Regulatory Mechanisms of the Vertebrate Segmentation Clock. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-493097
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493097