Pulmonary Embolism Related to Amisulpride Treatment : A Case Report
Joint Authors
Skokou, Maria
Gourzis, Philippos
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Venous thromboembolism has been associated with antipsychotic drugs, but the underlying mechanisms are largely unknown.
Hypotheses that have been made include body weight gain, sedation, enhanced platelet aggregation, increased levels of antiphospholipid antibodies, hyperhomocysteinemia, whereas hyperprolactinemia has recently attracted attention as a potential contributing factor.
The highest risk has been demonstrated for clozapine, olanzapine, and low-potency first-generation antipsychotics; however, presently there is no data for amisulpride.
In the present paper we describe a case of pulmonary embolism in a female bipolar patient, receiving treatment with amisulpride, aripiprazole, and paroxetine.
Although a contribution of aripiprazole and paroxetine cannot completely be ruled out, the most probable factor underlying the thromboembolic event seems to be hyperprolactinemia, which was caused by amisulpride treatment.
Increased plasma levels of prolactin should probably be taken into account during the monitoring of antipsychotic treatment as well as in future research concerning venous thromboembolism in psychiatric settings.
American Psychological Association (APA)
Skokou, Maria& Gourzis, Philippos. 2013. Pulmonary Embolism Related to Amisulpride Treatment : A Case Report. Case Reports in Psychiatry،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-493124
Modern Language Association (MLA)
Skokou, Maria& Gourzis, Philippos. Pulmonary Embolism Related to Amisulpride Treatment : A Case Report. Case Reports in Psychiatry No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-493124
American Medical Association (AMA)
Skokou, Maria& Gourzis, Philippos. Pulmonary Embolism Related to Amisulpride Treatment : A Case Report. Case Reports in Psychiatry. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-493124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493124