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Alterations in Nitric Oxide Synthase in the Aged CNS
Joint Authors
Huh, Youngbuhm
Na, Changhyun
Jung, Junyang
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Aging is associated with neuronal loss, gross weight reduction of the brain, and glial proliferation in the cortex, all of which lead to functional changes in the brain.
It is known that oxidative stress is a critical factor in the pathogenesis of aging; additionally, growing evidence suggests that excessive nitric oxide (NO) production contributes to the aging process.
However, it is still unclear how NO plays a role in the aging process.
This paper describes age-related changes in the activity of NADPH-diaphorase (NADPH-d), a marker for neurons containing nitric oxide synthase (NOS), in many CNS regions.
Understanding these changes may provide a novel perspective in identifying the aging mechanism.
American Psychological Association (APA)
Jung, Junyang& Na, Changhyun& Huh, Youngbuhm. 2012. Alterations in Nitric Oxide Synthase in the Aged CNS. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-493127
Modern Language Association (MLA)
Jung, Junyang…[et al.]. Alterations in Nitric Oxide Synthase in the Aged CNS. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-493127
American Medical Association (AMA)
Jung, Junyang& Na, Changhyun& Huh, Youngbuhm. Alterations in Nitric Oxide Synthase in the Aged CNS. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-493127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493127