Clinical Characteristics of Recurrent Nasopharyngeal Carcinoma in High-Incidence Area
Joint Authors
Lu, Tai-Xiang
Huang, Ying
Li, Jia-Xin
Han, Fei
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
To describe the clinical characteristics of the patients who suffered from relapse after conventional irradiation for nasopharyngeal carcinoma (NPC).
Methods.
Three hundred and fifty-one consecutive patients with first-time recurrent NPC between January 1999 and July 2005 were included.
The patients’ clinical data were reviewed, including recurrent interval time, symptoms, signs, imaging characteristics, pathologic features, and restaging.
Results.
The median interval of relapse was 26.0 months.
The most common symptoms in symptomatic patients were nasal bloody discharge (37.9%) and headache (31.1%).
Local recurrence alone accounted for 73.5%.
Most patients were restaged as stage III (23.1%) and stage IV (51.1%).
Subgroup analysis suggested a significantly higher proportion of the long-latent relapses originated from early primary.
A series of postreirradiation complications were more frequent in patients with longer latency at reception.
Conclusions.
Most recurrent nasopharyngeal carcinoma is advanced disease.
Patients with different recurrent interval time show different nature behavior.
American Psychological Association (APA)
Li, Jia-Xin& Lu, Tai-Xiang& Huang, Ying& Han, Fei. 2012. Clinical Characteristics of Recurrent Nasopharyngeal Carcinoma in High-Incidence Area. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493203
Modern Language Association (MLA)
Li, Jia-Xin…[et al.]. Clinical Characteristics of Recurrent Nasopharyngeal Carcinoma in High-Incidence Area. The Scientific World Journal No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-493203
American Medical Association (AMA)
Li, Jia-Xin& Lu, Tai-Xiang& Huang, Ying& Han, Fei. Clinical Characteristics of Recurrent Nasopharyngeal Carcinoma in High-Incidence Area. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493203
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493203