Course of Antibody Response in Lyme Borreliosis Patients before and after Therapy
Joint Authors
Aberer, Elisabeth
Schwantzer, Gerold
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The early immune response (IR) in European Lyme borreliosis patients has not yet been studied in detail.
The aim of the study was to analyse retrospectively the antibody development in 61 erythema migrans (EMs) patients depending on the duration of infection from tick bite by using a whole-cell lysate B.
garinii immunoblot.
The evolution of antibodies proved to be undulatory in untreated patients with two peaks for IgM at weeks 5 and 9 and for IgG at weeks 4 and 8.
The analysis of IR courses after therapy identified patients constantly seropositive or seronegative and patients with repeated seroconversions with a switch, disappearance, or reappearance of anti-23 kD or anti-39 kD antibodies during the one-year period.
We suggest that the antibody production in EM patients may be missed due to an undulatory IR.
This phenomenon might be an as yet insufficiently researched aspect in Lyme borreliosis.
American Psychological Association (APA)
Aberer, Elisabeth& Schwantzer, Gerold. 2012. Course of Antibody Response in Lyme Borreliosis Patients before and after Therapy. ISRN Immunology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-493206
Modern Language Association (MLA)
Aberer, Elisabeth& Schwantzer, Gerold. Course of Antibody Response in Lyme Borreliosis Patients before and after Therapy. ISRN Immunology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-493206
American Medical Association (AMA)
Aberer, Elisabeth& Schwantzer, Gerold. Course of Antibody Response in Lyme Borreliosis Patients before and after Therapy. ISRN Immunology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-493206
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493206