The Properties of Binding Sites of miR-619-5p, miR-5095, miR-5096, and miR-5585-3p in the mRNAs of Human Genes
Joint Authors
Pyrkova, Anna
Atambayeva, Shara
Niyazova, Raigul
Ivashchenko, Anatoly
Berillo, Olga
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The binding of 2,578 human miRNAs with the mRNAs of 12,175 human genes was studied.
It was established that miR-619-5p, miR-5095, miR-5096, and miR-5585-3p bind with high affinity to the mRNAs of the 1215, 832, 725, and 655 genes, respectively.
These unique miRNAs have binding sites in the coding sequences and untranslated regions of mRNAs.
The mRNAs of many genes have multiple miR-619-5p, miR-5095, miR-5096, and miR-5585-3p binding sites.
Groups of mRNAs in which the ordering of the miR-619-5p, miR-5095, miR-5096, and miR-5585-3p binding sites differ were established.
The possible functional and evolutional properties of unique miRNAs are discussed.
American Psychological Association (APA)
Ivashchenko, Anatoly& Berillo, Olga& Pyrkova, Anna& Niyazova, Raigul& Atambayeva, Shara. 2014. The Properties of Binding Sites of miR-619-5p, miR-5095, miR-5096, and miR-5585-3p in the mRNAs of Human Genes. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-493270
Modern Language Association (MLA)
Ivashchenko, Anatoly…[et al.]. The Properties of Binding Sites of miR-619-5p, miR-5095, miR-5096, and miR-5585-3p in the mRNAs of Human Genes. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-493270
American Medical Association (AMA)
Ivashchenko, Anatoly& Berillo, Olga& Pyrkova, Anna& Niyazova, Raigul& Atambayeva, Shara. The Properties of Binding Sites of miR-619-5p, miR-5095, miR-5096, and miR-5585-3p in the mRNAs of Human Genes. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-493270
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493270