The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer : A Model System within Bone Marrow
Joint Authors
Reddy, Bobby Y.
Rameshwar, Pranela
Lim, Philip K.
Silverio, Kimberly
Won, Brian Wong
Patel, Shyam A.
Source
International Journal of Breast Cancer
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Despite diagnostic advances, breast cancer remains the most prevalent cancer among women in the United States.
The armamentarium of treatment options for metastatic disease is limited and mostly ineffective with regards to eradicating cancer.
However, there have been novel findings in the recent literature that substantiate the function of the microenvironment in breast cancer progression and the support of metastasis to tertiary sites such as bone marrow.
The uncovered significance of the microenvironment in the pathophysiology of breast cancer metastasis has served to challenge previously widespread theories and introduce new perspectives for the future research to eradicate breast cancer.
This paper delineates the current understanding of the molecular mechanisms involved in the interactions between breast cancer cells and the microenvironment in progression, metastasis, and dormancy.
The information, in addition to other mechanisms described in bone marrow, is discussed in the paper.
American Psychological Association (APA)
Reddy, Bobby Y.& Lim, Philip K.& Silverio, Kimberly& Patel, Shyam A.& Won, Brian Wong& Rameshwar, Pranela. 2012. The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer : A Model System within Bone Marrow. International Journal of Breast Cancer،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-493365
Modern Language Association (MLA)
Reddy, Bobby Y.…[et al.]. The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer : A Model System within Bone Marrow. International Journal of Breast Cancer No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-493365
American Medical Association (AMA)
Reddy, Bobby Y.& Lim, Philip K.& Silverio, Kimberly& Patel, Shyam A.& Won, Brian Wong& Rameshwar, Pranela. The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer : A Model System within Bone Marrow. International Journal of Breast Cancer. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-493365
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493365