PPARs and Female Reproduction : Evidence from Genetically Manipulated Mice
Joint Authors
Zhang, Dongjuan
Guan, Youfei
Zhou, Yunfeng
Chen, Lihong
Yang, Jichun
Huo, Ming
Zhang, Xiaoyan
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear receptors controlling many important physiological processes, including lipid and glucose metabolism, energy homeostasis, inflammation, as well as cell proliferation and differentiation.
In the past decade, intensive study of PPARs has shed novel insight into prevention and treatment of dyslipidemia, insulin resistance, and type 2 diabetes.
Recently, a large body of research revealed that PPARs are also functionally expressed in reproductive organs and various parts of placenta during pregnancy, which strongly suggests that PPARs might play a critical role in reproduction and development, in addition to their central actions in energy homeostasis.
In this review, we summarize recent findings elucidating the role of PPARs in female reproduction, with particular focus on evidence from gene knockout and transgenic animal model study.
American Psychological Association (APA)
Yang, Jichun& Chen, Lihong& Zhang, Xiaoyan& Zhou, Yunfeng& Zhang, Dongjuan& Huo, Ming…[et al.]. 2008. PPARs and Female Reproduction : Evidence from Genetically Manipulated Mice. PPAR Research،Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-493424
Modern Language Association (MLA)
Yang, Jichun…[et al.]. PPARs and Female Reproduction : Evidence from Genetically Manipulated Mice. PPAR Research No. 2008 (2008), pp.1-8.
https://search.emarefa.net/detail/BIM-493424
American Medical Association (AMA)
Yang, Jichun& Chen, Lihong& Zhang, Xiaoyan& Zhou, Yunfeng& Zhang, Dongjuan& Huo, Ming…[et al.]. PPARs and Female Reproduction : Evidence from Genetically Manipulated Mice. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-493424
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493424