Fragmentation of Plasmid DNA Produced by Gamma Radiation : A Theoretical Approach
Joint Authors
Silva, R. A. S.
Arruda-Neto, J. D. T.
Nieto, L.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Breaks in DNA, resulting in fragmented parts, can be produced by ionizing radiation which, in turn, is the starting point in the search for novel physical aspects of DNA strands.
Double-strand breaks in particular cause disruption of the DNA strand, splitting it into several fragments.
In order to study effects produced by radiation in plasmid DNA, a new simple mechanical model for this molecule is proposed.
In this model, a Morse-like potential and a high-LET component are used to describe the DNA-radiation interaction.
Two power laws, used to fit results of the model, suggest that, firstly, distribution of fragment size is nonextensive and, secondly, that a transition phase is present in the DNA fragment distribution pattern.
American Psychological Association (APA)
Silva, R. A. S.& Arruda-Neto, J. D. T.& Nieto, L.. 2011. Fragmentation of Plasmid DNA Produced by Gamma Radiation : A Theoretical Approach. ISRN Biophysics،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-493640
Modern Language Association (MLA)
Silva, R. A. S.…[et al.]. Fragmentation of Plasmid DNA Produced by Gamma Radiation : A Theoretical Approach. ISRN Biophysics No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-493640
American Medical Association (AMA)
Silva, R. A. S.& Arruda-Neto, J. D. T.& Nieto, L.. Fragmentation of Plasmid DNA Produced by Gamma Radiation : A Theoretical Approach. ISRN Biophysics. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-493640
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493640