Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects : Implications for Analysis of Late HIV Diagnosis
Joint Authors
Sobrino-Vegas, Paz
Geskus, Ronald
Santos, Jesus
del Amo, Julia
Padilla, Belén
Segura, Ferrán
Moreno, Santiago
Pérez-Hoyos, Santiago
Rubio, Rafael
del Romero, Jorge
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
Since subjects may have been diagnosed before cohort entry, analysis of late HIV diagnosis (LD) is usually restricted to the newly diagnosed.
We estimate the magnitude and risk factors of LD in a cohort of seroprevalent individuals by imputing seroconversion dates.
Methods.
Multicenter cohort of HIV-positive subjects who were treatment naive at entry, in Spain, 2004–2008.
Multiple-imputation techniques were used.
Subjects with times to HIV diagnosis longer than 4.19 years were considered LD.
Results.
Median time to HIV diagnosis was 2.8 years in the whole cohort of 3,667 subjects.
Factors significantly associated with LD were: male sex; Sub-Saharan African, Latin-American origin compared to Spaniards; and older age.
In 2,928 newly diagnosed subjects, median time to diagnosis was 3.3 years, and LD was more common in injecting drug users.
Conclusions.
Estimates of the magnitude and risk factors of LD for the whole cohort differ from those obtained for new HIV diagnoses.
American Psychological Association (APA)
Sobrino-Vegas, Paz& Pérez-Hoyos, Santiago& Geskus, Ronald& Padilla, Belén& Segura, Ferrán& Rubio, Rafael…[et al.]. 2011. Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects : Implications for Analysis of Late HIV Diagnosis. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-493650
Modern Language Association (MLA)
Sobrino-Vegas, Paz…[et al.]. Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects : Implications for Analysis of Late HIV Diagnosis. AIDS Research and Treatment No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-493650
American Medical Association (AMA)
Sobrino-Vegas, Paz& Pérez-Hoyos, Santiago& Geskus, Ronald& Padilla, Belén& Segura, Ferrán& Rubio, Rafael…[et al.]. Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects : Implications for Analysis of Late HIV Diagnosis. AIDS Research and Treatment. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-493650
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493650