Preoperative Evaluation with fMRI of Patients with Intracranial Gliomas
Joint Authors
Verganelakis, Dimitrios
Lee, Gregory P.
Kapsalaki, Eftychia Z.
Toulas, Panagiotis
Chung, Indug
Fountas, Kostas N.
Fezoulidis, Ioannis
Robinson, Joe Sam
Kapsalakis, Ioannis Z.
Papadimitriou, Alexandros
Hadjigeorgiou, Georgios M.
Gotsis, Efstathios D.
Source
Radiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-12
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Introduction.
Aggressive surgical resection constitutes the optimal treatment for intracranial gliomas.
However, the proximity of a tumor to eloquent areas requires exact knowledge of its anatomic relationships to functional cortex.
The purpose of our study was to evaluate fMRI’s accuracy by comparing it to intraoperative cortical stimulation (DCS) mapping.
Material and Methods.
Eighty-seven patients, with presumed glioma diagnosis, underwent preoperative fMRI and intraoperative DCS for cortical mapping during tumor resection.
Findings of fMRI and DCS were considered concordant if the identified cortical centers were less than 5 mm apart.
Pre and postoperative Karnofsky Performance Scale and Spitzer scores were recorded.
A postoperative MRI was obtained for assessing the extent of resection.
Results.
The areas of interest were identified by fMRI and DCS in all participants.
The concordance between fMRI and DCS was 91.9% regarding sensory-motor cortex, 100% for visual cortex, and 85.4% for language.
Data analysis showed that patients with better functional condition demonstrated higher concordance rates, while there also was a weak association between tumor grade and concordance rate.
The mean extent of tumor resection was 96.7%.
Conclusions.
Functional MRI is a highly accurate preoperative methodology for sensory-motor mapping.
However, in language mapping, DCS remains necessary for accurate localization.
American Psychological Association (APA)
Kapsalakis, Ioannis Z.& Kapsalaki, Eftychia Z.& Gotsis, Efstathios D.& Verganelakis, Dimitrios& Toulas, Panagiotis& Hadjigeorgiou, Georgios M.…[et al.]. 2012. Preoperative Evaluation with fMRI of Patients with Intracranial Gliomas. Radiology Research and Practice،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-493863
Modern Language Association (MLA)
Kapsalakis, Ioannis Z.…[et al.]. Preoperative Evaluation with fMRI of Patients with Intracranial Gliomas. Radiology Research and Practice No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-493863
American Medical Association (AMA)
Kapsalakis, Ioannis Z.& Kapsalaki, Eftychia Z.& Gotsis, Efstathios D.& Verganelakis, Dimitrios& Toulas, Panagiotis& Hadjigeorgiou, Georgios M.…[et al.]. Preoperative Evaluation with fMRI of Patients with Intracranial Gliomas. Radiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-493863
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493863