Community-Associated Methicillin-Resistant Staphylococcus aureus Lacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid
Joint Authors
de Lencastre, Herminia
Gavino, Alexandra
Brito, Maria Joao
Bouchami, Ons
Miragaia, Maria
Varandas, Luis
Gouveia, Catarina
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging public health problem worldwide.
Severe invasive infections have been described, mostly associated with the presence of Panton-Valentine leukocidin (PVL).
In Portugal limited information exists regarding CA-MRSA infections.
In this study we describe the case of a previously healthy 12-year-old female, sport athlete, who presented to the hospital with acetabulofemoral septic arthritis, myositis, fasciitis, acetabulum osteomyelitis, and pneumonia.
The MRSA isolated from blood and synovial fluid was PVL negative and staphylococcal enterotoxin type P (SEP) and type L (SEL) positive, with a vancomycin MIC of 1.0 mg/L and resistant to clindamycin and ciprofloxacin.
The patient was submitted to multiple surgical drainages and started on vancomycin, rifampicin, and gentamycin.
Due to persistence of fever and no microbiological clearance, linezolid was started with improvement.
This is one of the few reported cases of severe invasive infection caused by CA-MRSA in Portugal, which was successfully treated with linezolid.
In spite of the severity of infection, the MRSA isolate did not produce PVL.
American Psychological Association (APA)
Gouveia, Catarina& Gavino, Alexandra& Bouchami, Ons& Miragaia, Maria& Varandas, Luis& de Lencastre, Herminia…[et al.]. 2013. Community-Associated Methicillin-Resistant Staphylococcus aureus Lacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid. Case Reports in Pediatrics،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-493865
Modern Language Association (MLA)
Gouveia, Catarina…[et al.]. Community-Associated Methicillin-Resistant Staphylococcus aureus Lacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid. Case Reports in Pediatrics No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-493865
American Medical Association (AMA)
Gouveia, Catarina& Gavino, Alexandra& Bouchami, Ons& Miragaia, Maria& Varandas, Luis& de Lencastre, Herminia…[et al.]. Community-Associated Methicillin-Resistant Staphylococcus aureus Lacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid. Case Reports in Pediatrics. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-493865
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493865