Hepatocellular Carcinoma : Current Management and Future Development—Improved Outcomes with Surgical Resection
Joint Authors
Kokudo, Norihiro
Hasegawa, Kiyoshi
Kishi, Yoji
Sugawara, Yasuhiko
Source
International Journal of Hepatology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Currently, surgical resection is the treatment strategy offering the best long-term outcomes in patients with hepatocellular carcinoma (HCC).
Especially for advanced HCC, surgical resection is the only strategy that is potentially curative, and the indications for surgical resection have expanded concomitantly with the technical advances in hepatectomy.
A major problem is the high recurrence rate even after curative resection, especially in the remnant liver.
Although repeat hepatectomy may prolong survival, the suitability may be limited due to multiple tumor recurrence or background liver cirrhosis.
Multimodality approaches combining other local ablation or systemic therapy may help improve the prognosis.
On the other hand, minimally invasive, or laparoscopic, hepatectomy has become popular over the last decade.
Although the short-term safety and feasibility has been established, the long-term outcomes have not yet been adequately evaluated.
Liver transplantation for HCC is also a possible option.
Given the current situation of donor shortage, however, other local treatments should be considered as the first choice as long as liver function is maintained.
Non-transplant treatment as a bridge to transplantation also helps in decreasing the risk of tumor progression or death during the waiting period.
The optimal timing for transplantation after HCC recurrence remains to be investigated.
American Psychological Association (APA)
Kishi, Yoji& Hasegawa, Kiyoshi& Sugawara, Yasuhiko& Kokudo, Norihiro. 2011. Hepatocellular Carcinoma : Current Management and Future Development—Improved Outcomes with Surgical Resection. International Journal of Hepatology،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-493887
Modern Language Association (MLA)
Kishi, Yoji…[et al.]. Hepatocellular Carcinoma : Current Management and Future Development—Improved Outcomes with Surgical Resection. International Journal of Hepatology No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-493887
American Medical Association (AMA)
Kishi, Yoji& Hasegawa, Kiyoshi& Sugawara, Yasuhiko& Kokudo, Norihiro. Hepatocellular Carcinoma : Current Management and Future Development—Improved Outcomes with Surgical Resection. International Journal of Hepatology. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-493887
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493887