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The Effects of Subchronic Exposure to Metribuzin on Danio rerio
Joint Authors
Bedanova, Iveta
Štěpánová, Stanislava
Praskova, Eva
Pistekova, Vladimira
Škorič, Miša
Svobodova, Zdenka
Divisova, Lenka
Chromcova, Lucie
Zelnickova, Lenka
Plhalová, Lucie
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The aim of this study was to assess the impact of metribuzin in surface waters on fish under experimental conditions.
The effects of subchronic exposure to metribuzin on fish growth and the development of histopathological changes in selected organs (gill, kidney, liver) and on activity of some biochemical markers (CYP450, EROD) in Danio rerio were investigated during a 28-day toxicity test.
Juvenile growth tests were performed on D.
rerio according to OECD method number 215.
Fish at an initial age of 30 days were exposed to a range of metribuzin concentrations (1.5, 5, 16, 33, and 53 mg L−1).
Exposure to metribuzin at 53 mg L−1 was associated with increased mortality.
Negative effects with regard to total body weight, length, and the inhibition of specific growth rate were induced at concentrations of 33 and 53 mg L−1.
Histopathological examination revealed pathological lesions in the liver in pesticide-exposed fish only at the highest concentration of 53 mg L−1 of metribuzin.
Based on the results of growth rate, biochemical markers (CYP450, EROD), and histopathological examination, the lowest observed effect concentration (LOEC) value was 33 mg L−1 and the no observed effect concentration (NOEC) value was 16 mg L−1.
American Psychological Association (APA)
Plhalová, Lucie& Štěpánová, Stanislava& Praskova, Eva& Chromcova, Lucie& Zelnickova, Lenka& Divisova, Lenka…[et al.]. 2012. The Effects of Subchronic Exposure to Metribuzin on Danio rerio. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-493897
Modern Language Association (MLA)
Plhalová, Lucie…[et al.]. The Effects of Subchronic Exposure to Metribuzin on Danio rerio. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-493897
American Medical Association (AMA)
Plhalová, Lucie& Štěpánová, Stanislava& Praskova, Eva& Chromcova, Lucie& Zelnickova, Lenka& Divisova, Lenka…[et al.]. The Effects of Subchronic Exposure to Metribuzin on Danio rerio. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-493897
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493897