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Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay : The Impact of Decision Style in Women with Intermediate RS
Joint Authors
O'Neill, Suzanne C.
Sulayman, Nadiyah K.
Spellman, Elizabeth
Graves, Kristi D.
Schwartz, Marc D.
Peshkin, Beth N.
Isaacs, Claudine
Source
Journal of Cancer Epidemiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Multigene assays such as the 21-gene recurrence score (RS) quantify risk for recurrence and potential benefit from chemotherapy in early-stage, ER+ breast cancers.
Few studies have assessed the impact of testing on patient-reported outcomes such as cancer-related distress or quality of life.
The few studies that have assessed these outcomes do not consider potential modifiers, such as the patients’ level of involvement in the treatment decision-making process.
In the current study, 81 breast cancer patients who received the RS assay completed cross-sectional surveys.
We used linear multiple regression to assess whether test result, decision-making role (passive versus shared/active), and their interaction contributed to current levels of distress, quality of life, and decisional conflict.
There were no associations between these variables and test result or decision-making role.
However, women who received an intermediate RS and took a passive role in their care reported higher-cancer-related distress and cancer worry and lower quality of life than those who took a shared or active role.
These data should be confirmed in prospective samples, as these poorer outcomes could be amenable to intervention.
American Psychological Association (APA)
Sulayman, Nadiyah K.& Spellman, Elizabeth& Graves, Kristi D.& Peshkin, Beth N.& Isaacs, Claudine& Schwartz, Marc D.…[et al.]. 2012. Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay : The Impact of Decision Style in Women with Intermediate RS. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493907
Modern Language Association (MLA)
Sulayman, Nadiyah K.…[et al.]. Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay : The Impact of Decision Style in Women with Intermediate RS. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-493907
American Medical Association (AMA)
Sulayman, Nadiyah K.& Spellman, Elizabeth& Graves, Kristi D.& Peshkin, Beth N.& Isaacs, Claudine& Schwartz, Marc D.…[et al.]. Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay : The Impact of Decision Style in Women with Intermediate RS. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493907
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493907