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Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer
Joint Authors
Sreelekha, T. T.
Rose-James, Alphy
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Lung cancer accounts for the majority of cancer-related deaths worldwide of which non-small-cell lung carcinoma alone takes a toll of around 85%.
Platinum-based therapy is the stronghold for lung cancer at present.
The discovery of various molecular alterations that underlie lung cancer has contributed to the development of specifically targeted therapies employing specific mutation inhibitors.
Targeted chemotherapy based on molecular profiling has shown great promise in lung cancer treatment.
Various molecular markers with predictive and prognostic significance in lung cancer have evolved as a result of advanced research.
Testing of EGFR and Kras mutations is now a common practice among community oncologists, and more recently, ALK rearrangements have been added to this group.
This paper discusses various predictive and prognostic markers that are being investigated and have shown significant relevance which can be exploited for targeted treatment in lung cancer.
American Psychological Association (APA)
Rose-James, Alphy& Sreelekha, T. T.. 2012. Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer. Lung Cancer International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-494034
Modern Language Association (MLA)
Rose-James, Alphy& Sreelekha, T. T.. Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer. Lung Cancer International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-494034
American Medical Association (AMA)
Rose-James, Alphy& Sreelekha, T. T.. Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer. Lung Cancer International. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-494034
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494034