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Electroacupuncture of 2 Hz Has a Rewarding Effect : Evidence from a Conditioned Place Preference Study in Rats
Joint Authors
Chu, Ning-Ning
Zhang, Rong
Xia, Wei
Cui, Cai-Lian
Liang, Jing
Li, Yi-Jing
Han, Ji-Sheng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Electroacupuncture (EA) has been used to suppress heroin craving in addicts and the conditioned place preference (CPP) for morphine in the rat.
The question remained whether EA by itself will produce some rewarding effect.
This was investigated using the CPP procedure in the present study.
The results indicated that rats showed a significant preference to the 2 Hz EA-paired compartment.
This rewarding effect of EA was prevented by pre-treatment with the opioid receptor antagonist naloxone [2 mg kg−1, intraperitoneally (i.p.)], CB1 cannabinoid antagonist AM251 (3 μg per rat, intracerebroventricularly) or D1 dopamine receptor antagonist SCH23390 (0.1 mg kg−1, i.p.), respectively.
TempspacetempspaceIt is concluded that 2 Hz EA is capable of inducing CPP in the rat via the activation of the endogenous opioid-, cannabinoid- and dopamine-systems.
American Psychological Association (APA)
Xia, Wei& Chu, Ning-Ning& Liang, Jing& Li, Yi-Jing& Zhang, Rong& Han, Ji-Sheng…[et al.]. 2011. Electroacupuncture of 2 Hz Has a Rewarding Effect : Evidence from a Conditioned Place Preference Study in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-494111
Modern Language Association (MLA)
Xia, Wei…[et al.]. Electroacupuncture of 2 Hz Has a Rewarding Effect : Evidence from a Conditioned Place Preference Study in Rats. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-494111
American Medical Association (AMA)
Xia, Wei& Chu, Ning-Ning& Liang, Jing& Li, Yi-Jing& Zhang, Rong& Han, Ji-Sheng…[et al.]. Electroacupuncture of 2 Hz Has a Rewarding Effect : Evidence from a Conditioned Place Preference Study in Rats. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-494111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494111