Study on the Formation of Novel Threadlike Structure through Intravenous Injection of Heparin in Rats and Refined Observation in Minipigs
Joint Authors
Guo, Shun-Gen
Zhou, Wen-Ting
Zhang, Wei-Bo
Jia, Shu-Yong
Zhang, Yu-Qing
Tian, Yu-Ying
Jing, Xiang-Hong
Huang, Tao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To study if the novel threadlike structure (NTS) was caused by coagulation during injecting urethane intraperitoneally and the source of NTS.
Methods.
Twenty-two SD rats were anaesthetized by urethane injected intraperitoneally.
Heparin was injected at 5 minutes before the anaesthesia from femoral vein in 11 rats, and saline was given in the other 11 rats randomly.
Six Chinese minipigs were carried to look for NTS.
One sample was taken to be stained by DAPI/Phalloidin and observed by a laser scanning confocal microscope.
Results.
In the group of heparin, 10 rats were found to have NTS with appearance rate of 90.9%, and 9 rats were found to have NTS with the appearance rate of 80.1%.
Both groups have 1.81 average numbers of NTS in each rat without significant difference (P>0.05).
In the observation of pigs, the NTS was found to prolong from the serous membranes of abdominal wall and organ surface.
Histological observation showed elongated nuclei and alignment which is similar to the characteristics of PVS.
Conclusion.
There is no strong evidence to say that the NTS on organ surface was caused by coagulation of blood.
The source of NTS might be a prolonged structure from serous membrane in abdominal cavity during the development and more or less retained after birth.
American Psychological Association (APA)
Tian, Yu-Ying& Jing, Xiang-Hong& Guo, Shun-Gen& Jia, Shu-Yong& Zhang, Yu-Qing& Zhou, Wen-Ting…[et al.]. 2013. Study on the Formation of Novel Threadlike Structure through Intravenous Injection of Heparin in Rats and Refined Observation in Minipigs. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-494218
Modern Language Association (MLA)
Tian, Yu-Ying…[et al.]. Study on the Formation of Novel Threadlike Structure through Intravenous Injection of Heparin in Rats and Refined Observation in Minipigs. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-494218
American Medical Association (AMA)
Tian, Yu-Ying& Jing, Xiang-Hong& Guo, Shun-Gen& Jia, Shu-Yong& Zhang, Yu-Qing& Zhou, Wen-Ting…[et al.]. Study on the Formation of Novel Threadlike Structure through Intravenous Injection of Heparin in Rats and Refined Observation in Minipigs. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-494218
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494218