Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools
Joint Authors
Xu, Li-Wen
Chen, Jia-Lei
Yang, Ming
Ji, Guang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-23, 23 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-31
Country of Publication
Egypt
No. of Pages
23
Main Subjects
Abstract EN
The concept of “network target” has ushered in a new era in the field of traditional Chinese medicine (TCM).
As a new research approach, network pharmacology is based on the analysis of network models and systems biology.
Taking advantage of advancements in systems biology, a high degree of integration data analysis strategy and interpretable visualization provides deeper insights into the underlying mechanisms of TCM theories, including the principles of herb combination, biological foundations of herb or herbal formulae action, and molecular basis of TCM syndromes.
In this study, we review several recent developments in TCM network pharmacology research and discuss their potential for bridging the gap between traditional and modern medicine.
We briefly summarize the two main functional applications of TCM network models: understanding/uncovering and predicting/discovering.
In particular, we focus on how TCM network pharmacology research is conducted and highlight different computational tools, such as network-based and machine learning algorithms, and sources that have been proposed and applied to the different steps involved in the research process.
To make network pharmacology research commonplace, some basic network definitions and analysis methods are presented.
American Psychological Association (APA)
Yang, Ming& Chen, Jia-Lei& Xu, Li-Wen& Ji, Guang. 2013. Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-494267
Modern Language Association (MLA)
Yang, Ming…[et al.]. Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-23.
https://search.emarefa.net/detail/BIM-494267
American Medical Association (AMA)
Yang, Ming& Chen, Jia-Lei& Xu, Li-Wen& Ji, Guang. Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-494267
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494267