Soluble Host Defense Lectins in Innate Immunity to Influenza Virus
Joint Authors
Tate, Michelle D.
Reading, Patrick C.
Ng, Wy Ching
Brooks, Andrew G.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-16
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Host defenses against viral infections depend on a complex interplay of innate (nonspecific) and adaptive (specific) components.
In the early stages of infection, innate mechanisms represent the main line of host defense, acting to limit the spread of virus in host tissues prior to the induction of the adaptive immune response.
Serum and lung fluids contain a range of lectins capable of recognizing and destroying influenza A viruses (IAV).
Herein, we review the mechanisms by which soluble endogenous lectins mediate anti-IAV activity, including their role in modulating IAV-induced inflammation and disease and their potential as prophylactic and/or therapeutic treatments during severe IAV-induced disease.
American Psychological Association (APA)
Ng, Wy Ching& Tate, Michelle D.& Brooks, Andrew G.& Reading, Patrick C.. 2012. Soluble Host Defense Lectins in Innate Immunity to Influenza Virus. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-494290
Modern Language Association (MLA)
Ng, Wy Ching…[et al.]. Soluble Host Defense Lectins in Innate Immunity to Influenza Virus. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-494290
American Medical Association (AMA)
Ng, Wy Ching& Tate, Michelle D.& Brooks, Andrew G.& Reading, Patrick C.. Soluble Host Defense Lectins in Innate Immunity to Influenza Virus. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-494290
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494290