Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life
Joint Authors
Miura, Taichi
Kawabe, Masaharu
Ui, Rui
Kimura, Shou
Kon, Katsushi
Iimura, Touta
Muneoka, Katsumasa
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Two cases of patients experienced subsyndromal depression after manic or mixed hypomanic and depressive episodes due to bipolar I (case 1) and II (case 2) disorders prior to the use of lamotrigine.
Case 1 showed episodes of mood switching induced by antidepressants and seasonal mood instability.
Case 2 showed hippocampal atrophy and a persistent dull headache that preceded the use of lamotrigine.
Both were successfully treated with add-on lamotrigine therapy, and the dull headache was effectively treated with olanzapine.
Both patients improved in social activity and work performance after these add-on treatments.
Thus, add-on treatment with lamotrigine alone or in combination with olanzapine was an effective strategy to improve the quality of life in bipolar depression.
Subsyndromal depression that present after the disappearance of the manic or mixed state was suggested to be practical indication for the use of lamotrigine.
American Psychological Association (APA)
Muneoka, Katsumasa& Kon, Katsushi& Kawabe, Masaharu& Ui, Rui& Miura, Taichi& Iimura, Touta…[et al.]. 2012. Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-494614
Modern Language Association (MLA)
Muneoka, Katsumasa…[et al.]. Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life. Case Reports in Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-494614
American Medical Association (AMA)
Muneoka, Katsumasa& Kon, Katsushi& Kawabe, Masaharu& Ui, Rui& Miura, Taichi& Iimura, Touta…[et al.]. Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-494614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494614