Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin

Joint Authors

Sammynaiken, Ramaswami
Maley, Jason
Rempel, Ben
Gui, Bo
Reaney, Martin

Source

Journal of Biomedicine and Biotechnology

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-03-10

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

The kinetics, energetics, and structure of Cyclolinopeptide A binding with Human Serum Albumin were investigated with surface plasmon resonance and circular dichroism.

The complex is formed through slow recognition kinetics that is temperature sensitive in the range of 20°C–37°C.

The overall reaction was observed to be endothermic (ΔH=204 kJ mol−1) and entropy driven (ΔS=746 J mol−1K−1) with overall small changes to the tertiary structure.

American Psychological Association (APA)

Rempel, Ben& Gui, Bo& Maley, Jason& Reaney, Martin& Sammynaiken, Ramaswami. 2011. Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-494673

Modern Language Association (MLA)

Rempel, Ben…[et al.]. Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-494673

American Medical Association (AMA)

Rempel, Ben& Gui, Bo& Maley, Jason& Reaney, Martin& Sammynaiken, Ramaswami. Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin. Journal of Biomedicine and Biotechnology. 2011. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-494673

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-494673