Mumijo Traditional Medicine : Fossil Deposits from Antarctica (Chemical Composition and Beneficial Bioactivity)
Joint Authors
Menna, Marialuisa
Aiello, Anna
Vitalone, Rocco
Schröder, Heinz C.
Müller, Werner E. G.
Fattorusso, Ernesto
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Mumijo is a widely used traditional medicine, especially in Russia, Altai Mountains, Mongolia, Iran Kasachstan and in Kirgistan.
Mumijo preparations have been successfully used for the prevention and treatment of infectious diseases; they display immune-stimulating and antiallergic activity as well.
In the present study, we investigate the chemical composition and the biomedical potential of a Mumijo(-related) product collected from the Antarctica.
The yellow material originates from the snow petrels, Pagodroma nivea.
Extensive purification and chemical analysis revealed that the fossil samples are a mixture of glycerol derivatives.
In vitro experiments showed that the Mumijo extract caused in cortical neurons a strong neuroprotective effect against the apoptosis-inducing amyloid peptide fragment β-fragment 25–35 (Aβ25–35).
In addition, the fraction rich in glycerol ethers/wax esters displayed a significant growth-promoting activity in permanent neuronal PC12 cells.
It is concluded that this new Mumijo preparation has distinct and marked neuroprotective activity, very likely due to the content of glycerol ether derivatives.
American Psychological Association (APA)
Aiello, Anna& Fattorusso, Ernesto& Menna, Marialuisa& Vitalone, Rocco& Schröder, Heinz C.& Müller, Werner E. G.. 2011. Mumijo Traditional Medicine : Fossil Deposits from Antarctica (Chemical Composition and Beneficial Bioactivity). Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-494730
Modern Language Association (MLA)
Aiello, Anna…[et al.]. Mumijo Traditional Medicine : Fossil Deposits from Antarctica (Chemical Composition and Beneficial Bioactivity). Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-494730
American Medical Association (AMA)
Aiello, Anna& Fattorusso, Ernesto& Menna, Marialuisa& Vitalone, Rocco& Schröder, Heinz C.& Müller, Werner E. G.. Mumijo Traditional Medicine : Fossil Deposits from Antarctica (Chemical Composition and Beneficial Bioactivity). Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-494730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494730