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Role of G Protein-Coupled Receptors in Control of Dendritic Cell Migration
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Dendritic cells (DCs) are highly efficient antigen-presenting cells.
The migratory properties of DCs give them the capacity to be a sentinel of the body and the vital role in the induction and regulation of adaptive immune responses.
Therefore, it is important to understand the mechanisms in control of migration of DCs to lymphoid and nonlymphoid tissues.
This may provide us novel insight into the clinical treatment of diseases such as autoimmune disease, infectious disease, and tumor.
The chemotactic G protein-coupled receptors (GPCR) play a vital role in control of DCs migration.
Here, we reviewed the recent advances regarding the role of GPCR in control of migration of subsets of DCs, with a focus on the chemokine receptors.
Understanding subsets of DCs migration could provide a rational basis for the design of novel therapies in various clinical conditions.
American Psychological Association (APA)
Liu, Yuan& Shi, Guixiu. 2014. Role of G Protein-Coupled Receptors in Control of Dendritic Cell Migration. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-494744
Modern Language Association (MLA)
Liu, Yuan& Shi, Guixiu. Role of G Protein-Coupled Receptors in Control of Dendritic Cell Migration. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-494744
American Medical Association (AMA)
Liu, Yuan& Shi, Guixiu. Role of G Protein-Coupled Receptors in Control of Dendritic Cell Migration. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-494744
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494744