Hox Targets and Cellular Functions
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-26, 26 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-30
Country of Publication
Egypt
No. of Pages
26
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Diseases
Abstract EN
Hox genes are a group of genes that specify structures along the anteroposterior axis in bilaterians.
Although in many cases they do so by modifying a homologous structure with a different (or no) Hox input, there are also examples of Hox genes constructing new organs with no homology in other regions of the body.
Hox genes determine structures though the regulation of targets implementing cellular functions and by coordinating cell behavior.
The genetic organization to construct or modify a certain organ involves both a genetic cascade through intermediate transcription factors and a direct regulation of targets carrying out cellular functions.
In this review I discuss new data from genome-wide techniques, as well as previous genetic and developmental information, to describe some examples of Hox regulation of different cell functions.
I also discuss the organization of genetic cascades leading to the development of new organs, mainly using Drosophila melanogaster as the model to analyze Hox function.Erratum to “Hox Targets and Cellular Functions”dx.doi.org/10.1155/2014/529298
American Psychological Association (APA)
Sánchez-Herrero, Ernesto. 2013. Hox Targets and Cellular Functions. Scientifica،Vol. 2013, no. 2013, pp.1-26.
https://search.emarefa.net/detail/BIM-494745
Modern Language Association (MLA)
Sánchez-Herrero, Ernesto. Hox Targets and Cellular Functions. Scientifica No. 2013 (2013), pp.1-26.
https://search.emarefa.net/detail/BIM-494745
American Medical Association (AMA)
Sánchez-Herrero, Ernesto. Hox Targets and Cellular Functions. Scientifica. 2013. Vol. 2013, no. 2013, pp.1-26.
https://search.emarefa.net/detail/BIM-494745
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494745