Effector Caspases and Leukemia
Joint Authors
Source
International Journal of Cell Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes.
Fourteen mammalian caspases have been identified and can be divided into two groups: inflammatory caspases and apoptotic caspases.
Based on the structure and function, the apoptotic caspases are further grouped into initiator/apical caspases (caspase-2, -8, -9, and -10) and effector/executioner caspases (caspase-3, -6, and -7).
In this paper, we discuss what we have learned about the role of individual effector caspase in mediating both apoptotic and nonapoptotic events, with special emphasis on leukemia-specific oncoproteins in relation to effector caspases.
American Psychological Association (APA)
Lu, Ying& Chen, Guo-Qiang. 2011. Effector Caspases and Leukemia. International Journal of Cell Biology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-494754
Modern Language Association (MLA)
Lu, Ying& Chen, Guo-Qiang. Effector Caspases and Leukemia. International Journal of Cell Biology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-494754
American Medical Association (AMA)
Lu, Ying& Chen, Guo-Qiang. Effector Caspases and Leukemia. International Journal of Cell Biology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-494754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494754