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Antioxidant Stress and Anti-Inflammation of PPARα on Warm Hepatic Ischemia-Reperfusion Injury
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Hepatic ischemia-reperfusion (IR) injury is a serious clinical problem.
Minimizing the adverse effect of ischemia-reperfusion injury after liver surgery or trauma is an urgent need.
It has been proved that besides the effect of regulating the lipid and lipoprotein metabolism, PPARα also undertakes the task of organ protection.
In this paper, related literature has been summarized and we come to the conclusion that administration of PPARα agonists can strengthen the antioxidant and anti-inflammation defense system by the upregulation of the expression of antioxidant enzymes and inhibition of NF-κB activity.
This may provide a potential clinical treatment for hepatic ischemia-reperfusion injury.
American Psychological Association (APA)
Gao, Zhixin& Li, Yuan-Hai. 2012. Antioxidant Stress and Anti-Inflammation of PPARα on Warm Hepatic Ischemia-Reperfusion Injury. PPAR Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-494803
Modern Language Association (MLA)
Gao, Zhixin& Li, Yuan-Hai. Antioxidant Stress and Anti-Inflammation of PPARα on Warm Hepatic Ischemia-Reperfusion Injury. PPAR Research No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-494803
American Medical Association (AMA)
Gao, Zhixin& Li, Yuan-Hai. Antioxidant Stress and Anti-Inflammation of PPARα on Warm Hepatic Ischemia-Reperfusion Injury. PPAR Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-494803
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494803