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Fulminant Hepatic Failure Attributed to Ackee Fruit Ingestion in a Patient with Sickle Cell Trait
Joint Authors
Thung, Swan N.
Florman, Sander
Fiel, Maria Isabel
Scordi-Bello, Irini
Suh, Matthew
Yao, Jonathan
Grunes, Dianne E.
Source
Case Reports in Transplantation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a case of fulminant liver failure resulting in emergent liver transplantation following 3 weeks of nausea, vomiting, and malaise from Jamaican Vomiting Sickness.
Jamaican Vomiting Sickness is caused by ingestion of the unripe arils of the Ackee fruit, its seeds and husks.
It is characterized by acute gastrointestinal illness and hypoglycemia.
In severe cases, central nervous system depression can occur.
In previous studies, histologic sections taken from patients with Jamaican Vomiting Sickness have shown hepatotoxicity similar to that seen in Reye syndrome and/or acetaminophen toxicity.
We highlight macroscopic and microscopic changes in the liver secondary to hepatoxicity of Ackee fruit versus those caused by a previously unknown sickle cell trait.
We discuss the clinical variables and the synergistic hepatotoxic effect of Ackee fruit and ischemic injury from sickled red blood cells, causing massive hepatic necrosis in this patient.
American Psychological Association (APA)
Grunes, Dianne E.& Scordi-Bello, Irini& Suh, Matthew& Florman, Sander& Yao, Jonathan& Fiel, Maria Isabel…[et al.]. 2012. Fulminant Hepatic Failure Attributed to Ackee Fruit Ingestion in a Patient with Sickle Cell Trait. Case Reports in Transplantation،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-494834
Modern Language Association (MLA)
Grunes, Dianne E.…[et al.]. Fulminant Hepatic Failure Attributed to Ackee Fruit Ingestion in a Patient with Sickle Cell Trait. Case Reports in Transplantation No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-494834
American Medical Association (AMA)
Grunes, Dianne E.& Scordi-Bello, Irini& Suh, Matthew& Florman, Sander& Yao, Jonathan& Fiel, Maria Isabel…[et al.]. Fulminant Hepatic Failure Attributed to Ackee Fruit Ingestion in a Patient with Sickle Cell Trait. Case Reports in Transplantation. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-494834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494834