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Quality of Life and Utility in Patients with Metastatic Soft Tissue and Bone Sarcoma : The Sarcoma Treatment and Burden of Illness in North America and Europe (SABINE) Study
Joint Authors
Leahy, Michael
Blay, Jean-Yves
García del Muro, Xavier
Wang, Jingshu
Ferrari, Stefano
Gelderblom, Hans
Krishna, Arun
Reichardt, Peter
Eriksson, Jennifer
Staddon, Arthur
Martin, Javier
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-20
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The aim of the study was to assess health-related quality of life (HRQoL) among metastatic soft tissue (mSTS) or bone sarcoma (mBS) patients who had attained a favourable response to chemotherapy.
We employed the EORTC QLQ-C30, the 3-item Cancer-Related Symptoms Questionnaire, and the EQ-5D instrument.
HRQoL was evaluated overall and by health state in 120 mSTS/mBS patients enrolled in the SABINE study across nine countries in Europe and North America.
Utility was estimated from responses to the EQ-5D instrument using UK population-based weights.
The mean EQ-5D utility score was 0.69 for the pooled patient sample with little variation across health states.
However, patients with progressive disease reported a clinically significant lower utility (0.56).
Among disease symptoms, pain and respiratory symptoms are common.
This study showed that mSTS/mBS is associated with reduced HRQoL and utility among patients with metastatic disease.
American Psychological Association (APA)
Reichardt, Peter& Leahy, Michael& García del Muro, Xavier& Ferrari, Stefano& Martin, Javier& Gelderblom, Hans…[et al.]. 2012. Quality of Life and Utility in Patients with Metastatic Soft Tissue and Bone Sarcoma : The Sarcoma Treatment and Burden of Illness in North America and Europe (SABINE) Study. Sarcoma،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-494912
Modern Language Association (MLA)
Reichardt, Peter…[et al.]. Quality of Life and Utility in Patients with Metastatic Soft Tissue and Bone Sarcoma : The Sarcoma Treatment and Burden of Illness in North America and Europe (SABINE) Study. Sarcoma No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-494912
American Medical Association (AMA)
Reichardt, Peter& Leahy, Michael& García del Muro, Xavier& Ferrari, Stefano& Martin, Javier& Gelderblom, Hans…[et al.]. Quality of Life and Utility in Patients with Metastatic Soft Tissue and Bone Sarcoma : The Sarcoma Treatment and Burden of Illness in North America and Europe (SABINE) Study. Sarcoma. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-494912
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494912