Different Impacts of Metabolic Syndrome Components on Insulin Resistance in Type 2 Diabetes
Author
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To examine the different impacts of MS components on insulin resistance in type 2 diabetes.
Methods.
A number of subjects (144) who met the criteria of (1) age between 30 and 75 years, (2) had type 2 diabetes for more than one year, and (3) taking gliclazide and metformin for more than 6 months were enrolled.
All subjects were assigned to one of the four HOMA index categories.
The HOMA index quartile 4 denotes the highest insulin resistance.
The main outcome evaluated is the odds ratios (ORs) of different MS components on HOMA index quartile 4.
The characteristics in HOMA index quartiles and groups of nonmetabolic syndrome (NMS; number of components < 2), metabolic syndrome A (MSA; number of components = 2), and metabolic syndrome B (MSB; number of components > 2) were also evaluated.
Results.
The results showed that both MSA and MSB groups had higher ORs (5.9 and 13.8 times, resp.) than the NMS group; and that subjects with large waist circumference (LWC) and high triglyceride (HTG) level have higher ORs (6.1 and 2.6 times, resp.) in developing higher insulin resistance than normal control subjects.
Conclusion.
Type 2 diabetic patients with greater number of MS components have higher ORs in developing increased insulin resistance.
American Psychological Association (APA)
Hsu, Chung-Hua. 2013. Different Impacts of Metabolic Syndrome Components on Insulin Resistance in Type 2 Diabetes. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-494929
Modern Language Association (MLA)
Hsu, Chung-Hua. Different Impacts of Metabolic Syndrome Components on Insulin Resistance in Type 2 Diabetes. International Journal of Endocrinology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-494929
American Medical Association (AMA)
Hsu, Chung-Hua. Different Impacts of Metabolic Syndrome Components on Insulin Resistance in Type 2 Diabetes. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-494929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494929