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Targeted Therapy in Ovarian Cancer
Joint Authors
Fruehauf, John P.
Willmott, Lyndsay J.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-14
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Ovarian cancer is the most common cause of mortality of tumors from gynecologic origin and is often diagnosed after patients have already progressed to advanced disease stage.
The current standard of care for treatment of ovarian cancer includes cytoreductive surgery followed by adjuvant chemotherapy.
Unfortunately, many patients will recur and ultimately die from their disease.
Targeted therapies have been evaluated in ovarian cancer as a method to overcome resistant disease.
Angiogenesis inhibitors have shown success in many tumor types and have also demonstrated promise in trials involving patients with ovarian cancer.
PARP inhibitors may be potentially active agents in patients with BRCA-associated ovarian cancer.
Trials that have evaluated combinations of targeted agents have often revealed untoward toxicities, thus tempering enthusiasm for this approach.
American Psychological Association (APA)
Willmott, Lyndsay J.& Fruehauf, John P.. 2010. Targeted Therapy in Ovarian Cancer. Journal of Oncology،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-494935
Modern Language Association (MLA)
Willmott, Lyndsay J.& Fruehauf, John P.. Targeted Therapy in Ovarian Cancer. Journal of Oncology No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-494935
American Medical Association (AMA)
Willmott, Lyndsay J.& Fruehauf, John P.. Targeted Therapy in Ovarian Cancer. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-494935
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-494935