![](/images/graphics-bg.png)
Laparoscopic Diagnosis and Laparoscopic Hyperthermic Intraoperative Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei Detected by CT Examination
Joint Authors
Hirano, Masamitsu
Ichinose, Masumi
Matsuda, Takayuki
Mizumoto, Akiyoshi
Yonemura, Yutaka
Canbay, Emel
Takao, Nobuyuki
Togawa, Tuyoshi
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Patients with early stage of pseudomyxoma peritonei (PMP) are sometimes difficult to diagnose the primary sites and intraperitoneal spread of tumor and to perform a cytological study.
Methods.
Patients without a definitive diagnosis and with unknown extent of peritoneal spread of tumor underwent laparoscopy.
Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) was administered as part of the same intervention.
The results of treatment were evaluated at the time of second-look laparotomy (SLL) as a subsequent intervention.
Results.
Eleven patients were managed by diagnostic laparoscopy followed by laparoscopic HIPEC (LHIPEC).
The operation time of laparoscopic examination and LHIPEC was 177 ± 26 min (range 124–261 min).
No intraoperative complication was experienced.
The peritoneal carcinomatosis index (PCI) score by laparoscopic observation was 16.5 ± 6.4 (range 0–30).
One patient with localized pseudomyxoma peritonei (PMP) mucocele did not received LHIPEC; the other 10 patients with peritoneal metastases (PM) were treated with LHIPEC.
After LHIPEC, ascites disappeared in 2 cases and decreased in the amount in the other 8 cases.
Nine patients underwent SLL and cytoreductive surgery (CRS) combined with HIPEC.
The duration between LHIPEC and SLL ranged from 40 to 207 days (97 ± 40 days).
The PCI at the SLL ranged from 4 to 27 (12.9 ± 7.1).
The PCI at the time of SLL decreased as compared to PCI at the time of diagnostic laparotomy in 7 of 9 patients.
Median follow-up period is 22 months (range 7–35).
All 11 patients are alive.
Conclusion.
The early results suggest that laparoscopic diagnosis combined with LHIPEC is useful to determine the surgical treatment plan and reduce the tumor burden before definitive CRS at SLL.
American Psychological Association (APA)
Hirano, Masamitsu& Yonemura, Yutaka& Canbay, Emel& Ichinose, Masumi& Togawa, Tuyoshi& Matsuda, Takayuki…[et al.]. 2012. Laparoscopic Diagnosis and Laparoscopic Hyperthermic Intraoperative Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei Detected by CT Examination. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-495004
Modern Language Association (MLA)
Hirano, Masamitsu…[et al.]. Laparoscopic Diagnosis and Laparoscopic Hyperthermic Intraoperative Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei Detected by CT Examination. Gastroenterology Research and Practice No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-495004
American Medical Association (AMA)
Hirano, Masamitsu& Yonemura, Yutaka& Canbay, Emel& Ichinose, Masumi& Togawa, Tuyoshi& Matsuda, Takayuki…[et al.]. Laparoscopic Diagnosis and Laparoscopic Hyperthermic Intraoperative Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei Detected by CT Examination. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-495004
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495004