Tumor Necrosis Factor-Alpha −308 G>A Polymorphism, Adherence to Mediterranean Diet, and Risk of OverweightObesity in Young Women
Joint Authors
Adornetto, Veronica
Marchese, Anna Elisa
Barchitta, Martina
Agodi, Antonella
Quattrocchi, Annalisa
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The present study was conducted in order to (i) characterize the adherence to the Mediterranean diet (MD) pattern and fatty acids (FAs) intakes and (ii) explore interactions between TNFA −308 G>A polymorphism and adherence to MD and FAs intakes, respectively, on overweight/obesity risk.
From 2010 to 2013, 380 healthy women were enrolled, and MD score (MDS) and FAs intakes were evaluated by a Food Frequencies Questionnaire in relation to nutritional status.
TNFA −308 G/A polymorphism was characterized using PCR-RFLP.
A total of 32.6% of women were overweight or obese.
Lower mean MDS values were more observed in the younger age group than in the older age group (3.60 versus 4.45).
The risk of being overweight/obese was 3.5-fold increased due to poor adherence to MD and was about twofold increased in less educated women.
Furthermore, younger age was associated with poor adherence to MD.
No evidence for an independent effect of the polymorphism on overweight/obesity risk was found.
There was no evidence of biological interaction from the gene-diet interaction analyses.
Young women, less educated and with poor adherence to MD, are a target group for the nutritional interventions that aimed to control the obesity risk, thus improving the adherence to MD and particularly the intake of unsaturated FAs.
American Psychological Association (APA)
Barchitta, Martina& Quattrocchi, Annalisa& Adornetto, Veronica& Marchese, Anna Elisa& Agodi, Antonella. 2014. Tumor Necrosis Factor-Alpha −308 G>A Polymorphism, Adherence to Mediterranean Diet, and Risk of OverweightObesity in Young Women. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-495159
Modern Language Association (MLA)
Barchitta, Martina…[et al.]. Tumor Necrosis Factor-Alpha −308 G>A Polymorphism, Adherence to Mediterranean Diet, and Risk of OverweightObesity in Young Women. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-495159
American Medical Association (AMA)
Barchitta, Martina& Quattrocchi, Annalisa& Adornetto, Veronica& Marchese, Anna Elisa& Agodi, Antonella. Tumor Necrosis Factor-Alpha −308 G>A Polymorphism, Adherence to Mediterranean Diet, and Risk of OverweightObesity in Young Women. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-495159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495159