Thyroid Dysfunction and Autoantibodies Association with Hypertensive Disorders during Pregnancy
Joint Authors
Nekuie, Sepideh
Solati, Mehrdad
Sobhani, Alireza
Jahromi, Elham Kazemi
Alavi, Azin
Jahanlou, Alireza Shahab
Karmostaji, Hoda
Adabi, Khadijeh
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Thyroid dysfunction and autoimmunity are relatively common in reproductive age and have been associated with adverse health outcomes for both mother and child, including hypertensive disorders during pregnancy.
Objective.
To survey the relation between thyroid dysfunction and autoimmunity and incidence and severity of pregnancy-induced hypertensive disorders.
Method.
In this case control study 48 hypertensive patients in 4 subgroups (gestational hypertension, mild preeclampsia, severe preeclampsia, eclampsia) and 50 normotensive ones were studied.
The samples were nulliparous and matched based on age and gestational age and none of them had previous history of hypertensive or thyroid disorders and other underlying systemic diseases or took medication that might affect thyroid function.
Their venous blood samples were collected using electrochemiluminescence and ELISA method and thyroid hormones and TSH and autoantibodies were measured.
Results.
Hypertensive patients had significant lower T3 concentration compared with normotensive ones with mean T3 values 152.5±48.93 ng/dL, 175.36±58.07 ng/dL respectively.
Anti-TPO concentration is higher in control group 6.07±9.02 IU/mL compared with 2.27±2.94 IU/mL in cases.
Conclusion.
The severity of preeclampsia and eclampsia was not associated with thyroid function tests.
The only significant value was low T3 level among pregnancy, induced hypertensive patients.
American Psychological Association (APA)
Alavi, Azin& Adabi, Khadijeh& Nekuie, Sepideh& Jahromi, Elham Kazemi& Solati, Mehrdad& Sobhani, Alireza…[et al.]. 2012. Thyroid Dysfunction and Autoantibodies Association with Hypertensive Disorders during Pregnancy. Journal of Pregnancy،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-495166
Modern Language Association (MLA)
Alavi, Azin…[et al.]. Thyroid Dysfunction and Autoantibodies Association with Hypertensive Disorders during Pregnancy. Journal of Pregnancy No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-495166
American Medical Association (AMA)
Alavi, Azin& Adabi, Khadijeh& Nekuie, Sepideh& Jahromi, Elham Kazemi& Solati, Mehrdad& Sobhani, Alireza…[et al.]. Thyroid Dysfunction and Autoantibodies Association with Hypertensive Disorders during Pregnancy. Journal of Pregnancy. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-495166
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495166