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Mediterranean Diet and Red Yeast Rice Supplementation for the Management of Hyperlipidemia in Statin-Intolerant Patients with or without Type 2 Diabetes
Joint Authors
Silvia, Burlina
Annunziata, Lapolla
Giovanni, Sartore
Valentini, Romina
Stefania, Ferraresso
Eugenio, Ragazzi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Lipid profile could be modified by Mediterranean diet (MD) and by red yeast rice (RYR).
We assessed the lipid-lowering effects of MD alone or in combination with RYR on dyslipidemic statin-intolerant subjects, with or without type 2 diabetes, for 24 weeks.
We evaluated the low-density lipoprotein (LDL) cholesterol level, total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, triglyceride, liver enzyme, and creatinine phosphokinase (CPK) levels.
We studied 171 patients: 46 type 2 diabetic patients treated with MD alone (Group 1), 44 type 2 diabetic patients treated with MD associated with RYR (Group 2), 38 dyslipidemic patients treated with MD alone (Group 3), and 43 dyslipidemic patients treated with MD plus RYR (Group 4).
The mean percentage changes in LDL cholesterol from the baseline were -7.34±3.14% (P<0.05) for Group 1; -21.02±1.63% (P<0.001) for Group 2; -12.47±1.75% (P<0.001) for Group 3; and -22±2.19% (P<0.001) for Group 4 with significant intergroup difference (Group 1 versus Group 2, P<0.001; Group 3 versus Group 4, P>0.05).
No significant increase in AST, ALT, and CPK levels was observed in all groups.
Our results indicate that MD alone is effective in reducing LDL cholesterol levels in statin-intolerant patients with a presumably low cardiovascular risk, but associating MD with the administration of RYR improves patients’ LDL cholesterol levels more, and in patients with type 2 diabetes.Erratum to “Mediterranean Diet and Red Yeast Rice Supplementation for the Management of Hyperlipidemia in Statin-Intolerant Patients with or without Type 2 Diabetes”dx.doi.org/10.1155/2014/432141
American Psychological Association (APA)
Giovanni, Sartore& Silvia, Burlina& Eugenio, Ragazzi& Stefania, Ferraresso& Valentini, Romina& Annunziata, Lapolla. 2013. Mediterranean Diet and Red Yeast Rice Supplementation for the Management of Hyperlipidemia in Statin-Intolerant Patients with or without Type 2 Diabetes. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-495225
Modern Language Association (MLA)
Giovanni, Sartore…[et al.]. Mediterranean Diet and Red Yeast Rice Supplementation for the Management of Hyperlipidemia in Statin-Intolerant Patients with or without Type 2 Diabetes. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-495225
American Medical Association (AMA)
Giovanni, Sartore& Silvia, Burlina& Eugenio, Ragazzi& Stefania, Ferraresso& Valentini, Romina& Annunziata, Lapolla. Mediterranean Diet and Red Yeast Rice Supplementation for the Management of Hyperlipidemia in Statin-Intolerant Patients with or without Type 2 Diabetes. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-495225
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495225