Mucin Production and Mucous Cell Metaplasia in Otitis Media
Joint Authors
Huang, Jianmin
Hu, Xiaohua
Lin, Jizhen
Feng, Ling
Ye, Shengnan
Caye-Thomasen, Per
Kerschner, Joseph E.
Tono, Tetsuya
Zhang, Quan-An
Nakamura, Yoshihisa
Source
International Journal of Otolaryngology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-22
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Otitis media (OM) with mucoid effusion, characterized by mucous cell metaplasia/hyperplasia in the middle ear cleft and thick fluid accumulation in the middle ear cavity, is a subtype of OM which frequently leads to chronic OM in young children.
Multiple factors are involved in the developmental process of OM with mucoid effusion, especially disorders of mucin production resulting from middle ear bacterial infection and Eustachian tube dysfunction.
In this review, we will focus on several aspects of this disorder by analyzing the cellular and molecular events such as mucin production and mucous cell differentiation in the middle ear mucosa with OM.
In addition, infectious agents, mucin production triggers, and relevant signaling pathways will be discussed.
American Psychological Association (APA)
Lin, Jizhen& Caye-Thomasen, Per& Tono, Tetsuya& Zhang, Quan-An& Nakamura, Yoshihisa& Feng, Ling…[et al.]. 2012. Mucin Production and Mucous Cell Metaplasia in Otitis Media. International Journal of Otolaryngology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-495319
Modern Language Association (MLA)
Lin, Jizhen…[et al.]. Mucin Production and Mucous Cell Metaplasia in Otitis Media. International Journal of Otolaryngology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-495319
American Medical Association (AMA)
Lin, Jizhen& Caye-Thomasen, Per& Tono, Tetsuya& Zhang, Quan-An& Nakamura, Yoshihisa& Feng, Ling…[et al.]. Mucin Production and Mucous Cell Metaplasia in Otitis Media. International Journal of Otolaryngology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-495319
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495319