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Evolution of Lysine Biosynthesis in the Phylum Deinococcus-Thermus
Joint Authors
Nishida, Hiromi
Nishiyama, Makoto
Source
International Journal of Evolutionary Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Thermus thermophilus biosynthesizes lysine through the α-aminoadipate (AAA) pathway: this observation was the first discovery of lysine biosynthesis through the AAA pathway in archaea and bacteria.
Genes homologous to the T.
thermophilus lysine biosynthetic genes are widely distributed in bacteria of the Deinococcus-Thermus phylum.
Our phylogenetic analyses strongly suggest that a common ancestor of the Deinococcus-Thermus phylum had the ancestral genes for bacterial lysine biosynthesis through the AAA pathway.
In addition, our findings suggest that the ancestor lacked genes for lysine biosynthesis through the diaminopimelate (DAP) pathway.
Interestingly, Deinococcus proteolyticus does not have the genes for lysine biosynthesis through the AAA pathway but does have the genes for lysine biosynthesis through the DAP pathway.
Phylogenetic analyses of D.
proteolyticus lysine biosynthetic genes showed that the key gene cluster for the DAP pathway was transferred horizontally from a phylogenetically distant organism.
American Psychological Association (APA)
Nishida, Hiromi& Nishiyama, Makoto. 2012. Evolution of Lysine Biosynthesis in the Phylum Deinococcus-Thermus. International Journal of Evolutionary Biology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495362
Modern Language Association (MLA)
Nishida, Hiromi& Nishiyama, Makoto. Evolution of Lysine Biosynthesis in the Phylum Deinococcus-Thermus. International Journal of Evolutionary Biology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-495362
American Medical Association (AMA)
Nishida, Hiromi& Nishiyama, Makoto. Evolution of Lysine Biosynthesis in the Phylum Deinococcus-Thermus. International Journal of Evolutionary Biology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495362
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495362